US pharmacy chains to stop sale of Zantac
Pharmacy chains in the US have moved to stop selling Zantac – a drug for heartburn – and its generic versions following the announcement by the (US) Food and Drug Administration (FDA) that a suspected cancer-causing impurity has been detected in the popular over-the-counter antacid.
The Swiss Pharmaceutical giant, Novartis had earlier on Sept. 18, stopped the worldwide distribution of its own brand of the drug as a precautionary measure, since the announcement by FDA that some medicines containing ranitidine, including those sold under the brand Zantac, have been found to contain “low levels” of an impurity called N-nitrosodimethylamine (NDMA), a probable human carcinogen.
Scientists say NDMA is likely capable of increasing cancer risk when taken in high doses over a long period of time. It can cause tumors in the liver and other organs in lab animals, and they are believed to be carcinogenic in humans.
NDMA can form during manufacturing if the chemical reactions used to make the drug are not carefully controlled, the FDA has said.
It is the same impurity that was discovered in some blood pressure medicines including valsartan and losartan last year, resulting in a global recall by manufacturers and drug retail outlets.
FDA also announced it was investigating the source of the contamination as well as the risk to patients and recommended that they talk to their doctors while those who take over-the-counter versions should consider switching to a different medication.
FDA was tipped off recently to the fact that NDMA was showing up in ranitidine drugs by an online pharmacy, Valisure which also filed a Citizen Petition urging the agency to recall all of the ranitidine drugs and set standards like it has with the blood pressure medicines.
About author
You might also like
Breast milk stops inflammation, combats infection
… new research reveals Human breast milk, which provides essential nutrients and antibodies to newborns, has long been known to play an important role in infant development and the immune
FG restates commitment to promoting oral health
Abuja – The Federal Government on Monday reiterated its determination to continue to promote oral health in the country through sensitization of the population on the gains of keeping their mouth
NCDC Launches public awareness campaign ‘6232’
The Nigeria Centre for Disease Control (NCDC) has announced the commencement of ‘Campaign 6232’. This is an activity to raise public awareness for the toll-free number ‘6232’ recently introduced by
0 Comments
No Comments Yet!
You can be first to comment this post!