Lassa fever kills 93 in Nigeria in less than two months

93 persons have been killed by Lassa fever in Nigeria in less than two months.

The nation recorded 420 confirmed cases of the disease between 21st January when it recorded its first case and 11th March, 2019.

Briefing newsmen in Abuja on Monday, Chief Executive Officer, National Centre for Disease Control, Dr. Chikwe Ihekweazu, said despite the deaths, there had been a decline in the number of new cases of Lassa fever recorded in the country.

Ihekweaze said following the large Lassa fever outbreak in 2018, the NCDC together with partners instituted five key measures to ensure improved preparedness in 2019.

He listed the measures to include training over one thousand health care workers in the six zones in the country on Lassa fever management, diagnosis and surveillance, together with the Irrua Specialist Teaching Hospital; prepositioning of treatment and diagnostic supplies to the 21 states that recorded cases in 2018, treatment centres and laboratories; publication of Lassa fever messages on three major newspapers, weekly radio shows on Radio Nigeria, and intensive community engagement.

Others are high level advocacy visits to State Governments, encouraging them to do more to prevent and respond to cases of Lassa fever; and developed new case management guidelines, initiated a Lassa fever Research Consortium and hosted and International Conference on Lassa Fever to share knowledge.

“Following the declaration of the 2019 outbreak, Rapid Response Teams (RRTs) comprising officers from the NCDC, Federal Ministry of Agriculture and Rural Development and Federal Ministry of Environment have supported the response in the high burden states of Edo, Ondo, Ebonyi, Plateau, Bauchi and Taraba states. In these states, NCDC has also supported full availability of drugs, personal protective equipment, laboratory reagents and other supplies required for case management and diagnosis of Lassa fever. This year, there has been no single stock-out reported in any state,” the Centre said.

The Centre had in January 2019 hosted first Lassa fever International Conference. “This brought together the largest gathering of researchers and professionals to discuss progress on Lassa fever. Importantly, Nigeria introduced her national Lassa fever research plan and has been recognised as one of the leading stakeholders in global Lassa fever research. Over the last six months, progress has been made in this area especially in discussions around Lassa fever vaccines. In the next one year, Nigeria is expected to be part of clinical trials towards the development of Lassa fever vaccines.”

“In 2018, genetic sequencing carried out at the Irrua Specialist Teaching Hospital showed that the virus circulating originated from the pool of lineages that have been in Nigeria since the first discovery. This year, early sequencing result shows similar findings. The preliminary results of 42 Lassa fever virus sequences indicate that rodent to human transmission, as observed in 2018, is still the dominant route of transmission. Therefore, there is a strong need to improve prevention measures especially around environmental sanitation.

“The progress recorded in the response to the 2019 Lassa fever outbreak including an early decline in the number of new cases and reduced case fatality have been attributed to various factors. This includes the early deployment of One-Health national RRTs, improvement of functions in Lassa fever treatment centres, revision of case management guidelines, enforcement of environmental sanitation in some states, introduction of the Infection Prevention and Control (IPC) ring strategy, targeted intensified risk communications activities, high level advocacy visits, operational research into response activities, amongst others.

“It is very important that Nigerians continue to practice preventive measures to avoid infection. Prevention of Lassa fever relies on promoting good community hygiene to discourage rodents from entering homes. Other effective measures include storing grains and other foodstuff in rodent-proof containers, proper disposal of garbage far from the home, maintaining clean households and frequent hand hygiene. All food should be well prepared, and family members should always be careful to avoid contact with blood and body fluids while caring for sick persons.”

 

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